Allometric Approaches to Clearance

Approach 1 Cl = a 7 Wb

(Neoteny)

Approach 2 Cl = a 7 Wb/MLP

Approach 3 Cl = a 7 Brb 7 Wc

Approach 4 Cl = a 7 Wb/Br

MLP = Maximum lifespan potential; Br = Brain weight

(Adapted from T. Lave et al., Clin. Pharmacokin. 36:211, 1999)

Previous slide

Next slide

Back to first slide

View graphic version