2 . FDA carcinogenicity study plans shorter term
Mechanistic studies, including bioavailability and markers of exposure and effect
DNA and protein adducts caused by acrylamide
- Adducts are reaction products between a chemical and either DNA or proteins
- Adducts can tell us
- How much exposure occurs and
- Help us understand the toxicology
- Adducts may be particularly useful in relating animal toxicity studies to potential risks for humans from acrylamide