1. Plans for Toxicokinetics data development

• FDA - National Center for Toxicological Research (NCTR)

  • DNA/protein adduct characterization and their relationship to effects and relevant external dose levels
  • Bioavailability

• CDC - National Center for Environmental Health (NCEH)

  • Biomarker-intake relationship in studies prior to NHANES

• Acrylamide monomer industry

  • Human dosing study, PbPk model development